Table 3.

Association Results of the Top Signals in Un-conditional Analysis, the GIANT Hits and Significant Variants for Analysis Conditional on the Top Signals in Our Data and the GIANT Hits

rs-number	Position	EA*	NEA*	Effect †	SE †	P	D	I2	Het-P	n	EAF*	HWE-p
- Conditional on rs6548238‡: GIANT GWAS Variant
rs186019316	601740	A	G	−1.37	0.6	1.95 × 10−4	--+	87	0.0004	3762	0.022	0.094
rs2867125	612827	T	C	0.04	0.6	3.97 × 10−1	+-+	0	0.6833	3880	0.177	0.018
rs7596758	648595	G	T	0.29	0.2	2.12 × 10−3	++-	69	0.0400	3927	0.288	0.104
- Conditional on rs2867125§: GIANT GWAS Variant
rs186019316	601740	A	G	−1.38	0.4	2.03 × 10−4	--+	88	0.0002	3635	0.022	0.094
rs6548238	624905	T	C	−0.39	0.6	5.40 × 10−2	---	0	0.4617	3780	0.175	0.076
rs7596758	648595	G	T	0.31	0.2	1.36 × 10−3	++-	74	0.0200	3765	0.288	0.104
- Conditional on rs7596758
rs6548238	624905	T	C	0.01	0.17	7.21 × 10−2	-+-	22	0.2792	3780	0.175	0.076
rs2867125	612827	T	C	−0.06	0.17	2.26 × 10−1	-+-	0	0.5230	3765	0.177	0.018

^*EA: Effect allele; NEA: non-effect allele; EAF: effect allele frequency

^†Effect and SE was obtained from analysis with sampling weight adjusted

^‡Variant identified from Willer et al. 2009⁶

^§Variant identified from Speiliotes et al. 2010⁵