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(A) Effects of UPC2 in resistant backgrounds on MICs and growth on YPD agar as determined by Etest. A confluent lawn of C. albicans was streaked prior to the addition of Etest strips and was then incubated for 48 h. (B) Effects of UPC2 in resistant backgrounds on the ability to grow on a solid medium containing fluconazole. From 4-fold serial dilutions of C. albicans strains, 2-μl aliquots were spotted onto YPD agar with (right) or without (left) 10 μg/ml FLC and were incubated for 48 h.
