TABLE 1.
C. albicans strains used in this study
| Strain | Designation | Strain backgrounda | Relevant characteristic(s) or genotypeb | Source or reference |
|---|---|---|---|---|
| SC5314 | SC5314 | N/A | UPC2-1/UPC2-2 | ATCC |
| Clinical isolate 2-79 | 2-79 | N/A | Susceptible isolate | 53 |
| Clinical isolate 12-99 | 12-99 | N/A | Resistant isolate | 53 |
| UPC2M4A | upc2Δ/Δ strain | SC5314 | upc2-1Δ::FRT/upc2-2Δ::FRT | 25 |
| UPC2M2K21A | upc2Δ/Δ+UPC2 strain | UPC2M2A | upc2-1Δ::FRT/UPC2S1-1-caSAT1 | 25 |
| 12-99UPC2A5C1A | 12-99upc2Δ/Δ | 12-99 | upc2Δ::FRT/upc2Δ::FRT | This study |
| 12-99UPC2A5C1A4A | 12-99upc2Δ/Δ+UPC2 | 12-99UPC2A5C1A | upc2Δ::FRT/UPC212-99-caSAT1 | This study |
| 10C1B1M1 | ERG11K143R mutant | SC5314 | ERG11K143R::FRT/ERG11K143R::FRT UPC2-1/UPC2-2 | This study |
| 10C1B1M1UPC2C9H | ERG11upc2Δ/Δ mutant | 10C1B1M1 | ERG11K143R::FRT/ERG11K143R::FRT upc2-1Δ::FRT/upc2-2Δ::FRT | This study |
| SCMRR1R34A | MRR1P683S mutant | SC5314 | MRR1P683S::FRT/MRR1P683S::FRT UPC2-1/UPC2-2 | 20 |
| Δupc2MRR1R34A | MRR1upc2Δ/Δ mutant | SCMRR1R34A | MRR1P683S::FRT/MRR1P683S::FRT upc2-1Δ::FRT/upc2-2Δ::FRT | 20 |
| SCTAC1R34A | TAC1G980E mutant | SC5314 | TAC1G980E::FRT/TAC1G980E::FRT UPC2-1/UPC2-2 | 32 |
| SCupc2TAC1R34A1A14A | TAC1upc2Δ/Δ mutant | SCTAC1R34A | TAC1G980E::FRT/TAC1G980E::FRT upc2-1Δ::FRT/upc2-2Δ::FRT | This study |
a
N/A, not applicable.
b
FRT, FLP recombination target.