TABLE 2.
Taxonomic coverage of primers designed by DegePrime as evaluated by the Probe Match tool in RDPa
Taxonomic group | No. of sequences | Coverage of primer: |
|||
---|---|---|---|---|---|
341F | 341′F | 515′F | 805R | ||
Bacteria | 1,534,872 | 0.96 | 0.93 | 0.93 | 0.90 |
Actinobacteria | 204,784 | 0.97 | 0.97 | 0.72 | 0.71 |
Aquificae | 1,279 | 0.97 | 0.97 | 0.97 | 0.95 |
Bacteroidetes | 182,923 | 0.97 | 0.97 | 0.97 | 0.96 |
Caldiserica | 263 | 0.98 | 0.98 | 0.00 | 0.97 |
Chlamydiae | 563 | 0.76 | 0.01 | 0.01 | 0.96 |
Chlorobi | 1,531 | 0.95 | 0.95 | 0.62 | 0.95 |
Chloroflexi | 25,804 | 0.89 | 0.76 | 0.96 | 0.35 |
Chrysiogenetes | 13 | 0.85 | 0.85 | 1.00 | 1.00 |
Deferribacteres | 734 | 0.99 | 0.99 | 0.98 | 0.96 |
Deinococcus-Thermus | 2,556 | 0.97 | 0.97 | 0.98 | 0.97 |
Dictyoglomi | 36 | 1.00 | 1.00 | 0.97 | 1.00 |
Elusimicrobia | 326 | 0.97 | 0.98 | 0.98 | 0.94 |
Fibrobacteres | 462 | 0.96 | 0.96 | 0.98 | 0.96 |
Fusobacteria | 10,194 | 0.95 | 0.95 | 0.97 | 0.97 |
Gemmatimonadetes | 2,152 | 0.98 | 0.98 | 0.97 | 0.93 |
Lentisphaerae | 1,978 | 0.94 | 0.00 | 0.98 | 0.96 |
Nitrospira | 2,258 | 0.98 | 0.98 | 0.97 | 0.95 |
Planctomycetes | 14,348 | 0.81 | 0.01 | 0.93 | 0.94 |
Proteobacteria | 454,358 | 0.98 | 0.98 | 0.97 | 0.94 |
Spirochaetes | 10,644 | 0.92 | 0.92 | 0.97 | 0.86 |
Synergistetes | 1,649 | 0.98 | 0.98 | 0.97 | 0.94 |
Tenericutes | 4,064 | 0.94 | 0.94 | 0.93 | 0.96 |
Thermodesulfobacteria | 166 | 0.96 | 0.96 | 0.96 | 0.99 |
Thermotogae | 777 | 0.97 | 0.97 | 0.97 | 0.94 |
BRC1 | 477 | 0.94 | 0.94 | 0.96 | 0.97 |
OD1 | 411 | 0.68 | 0.00 | 0.00 | 0.88 |
OP11 | 150 | 0.21 | 0.01 | 0.27 | 0.00 |
SR1 | 466 | 0.95 | 0.96 | 0.97 | 0.97 |
TM7 | 2,596 | 0.97 | 0.97 | 0.00 | 0.88 |
WS3 | 672 | 0.96 | 0.98 | 0.97 | 0.97 |
Armatimonadetes | 1,576 | 0.29 | 0.05 | 0.97 | 0.91 |
Verrucomicrobia | 12,387 | 0.98 | 0.00 | 0.96 | 0.93 |
Acidobacteria | 27,092 | 0.98 | 0.97 | 0.98 | 0.95 |
Firmicutes | 483,681 | 0.97 | 0.96 | 0.97 | 0.96 |
Cyanobacteria/Chloroplast | 30,775 | 0.93 | 0.93 | 0.98 | 0.95 |
Unclassified_Bacteria | 50,727 | 0.84 | 0.66 | 0.88 | 0.86 |
Archaea | 78,684 | 0.00 | 0.90 | 0.96 | 0.94 |
Crenarchaeota | 20,677 | 0.00 | 0.89 | 0.97 | 0.93 |
Euryarchaeota | 41,963 | 0.00 | 0.93 | 0.96 | 0.95 |
Korarchaeota | 221 | 0.00 | 0.93 | 0.95 | 0.93 |
Nanoarchaeota | 138 | 0.00 | 0.00 | 0.00 | 0.00 |
Thaumarchaeota | 0 | NA | NA | NA | NA |
Unclassified_Archaea | 15,685 | 0.00 | 0.85 | 0.96 | 0.93 |
The search was conducted against release 11, update 1, of RDP, including only sequences with good-quality scores that span E. coli positions 300 to 850. Primer sequences were the following: 341F, CCTACGGGNGGCWGCAG; 341′F, CCTAHGGGRBGCAGCAG; 515′F, GTGBCAGCMGCCGCGGTAA; 805R, GACTACHVGGGTATCTAATCC. NA, not applicable.