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. 2014 Aug;13(8):1026–1035. doi: 10.1128/EC.00043-14

TABLE 1.

PHD amino acid sequence comparison

Protein domainc Identity (%) with:
PFP1 NTO1 BRPF1a BRPF2b BRPF3 JADE-1 JADE-2 JADE-3
PFP1IV 66 70 70 66 50 46 52
NTO1IV 78 56 54 58 54 48 56
BRPF1III 90 74 96 86 50 50 50
BRPF2III 86 74 96 86 64 50 50
BRPF3III 82 74 90 92 50 50 52
JADE-1IV 66 66 68 68 64 92 82
JADE-2IV 64 64 66 66 62 98 82
JADE-3IV 64 68 68 68 64 96 94
a

Alternative names, BR140 and peregrin.

b

Alternative names, BRD1 and BRL.

c

Roman numerals indicate Epc-N classes. Proteins belonging to mainly histone 3-acetylating HAT complexes are indicated in boldface. GenBank accession numbers are as follows: NTO1, NP_015356; BRPF1, NP_001003694; BRPF2, XP_005261529; BRPF3, AAI17388; JADE-1, NP_955352; JADE-2, XP_005272000; and JADE-3, NP_055550. Sequences were aligned pairwise using the matrix BLOSUM62 of the European Molecular Biology Open Source Software Suite (http://www.ebi.ac.uk/tools/psa/emboss_needle/).