Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
NS5A amino acid substitutions in cDNA clones isolated from DCV-treated GT-6a-16 replicon cells
| Amino acid substitution | No. of clones with indicated amino acid substitution(s) at DCV selection concn of: |
|
|---|---|---|
| 1 nM | 10 nM | |
| Q24H | 3 | 0 |
| L31M | 2 | 6 |
| P32A | 0 | 1 |
| P32L | 0 | 9 |
| P32Q | 1 | 0 |
| P32S | 8 | 28 |
| T58A | 22 | 0 |
| T58N | 0 | 1 |
| T58S | 4 | 0 |
| Q24H-T58A | 1 | 0 |
| L31P-P32S | 1 | 0 |
| T58A-T93N | 1 | 0 |
| Total no. of clones | 43 | 45 |
