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. 2014 Sep;58(9):5609–5612. doi: 10.1128/AAC.02875-14

TABLE 1.

MIC/MEC values of nine antifungal drugs against 46 P. verrucosa strains

Strain group (no. of strains) and drug MIC/MEC (μg/ml)
Range 50% 90% Geometric mean
Total (n = 46)
    Fluconazole 8–256 32 64 55.826
    Flucytosine 2–256 16 64 32.609
    Amphotericin B 2–4 4 4 3.261
    Itraconazole 0.25–4 0.5 2 0.973
    Voriconazole 0.063–4 0.25 1 0.58
    Posaconazole 0.031–1 0.125 0.5 0.232
    Caspofungin 2–16 8 16 9.174
    Micafungin 0.5–32 4 16 8.63
    Terbinafine 0.002–1 0.125 0.25 0.152
Clinical (n = 31)
    Fluconazole 8–256 32 64 43.097
    Flucytosine 2–256 16 64 36.387
    Amphotericin B 2–4 4 4 3.29
    Itraconazole 0.25–1 0.5 0.5 0.476
    Voriconazole 0.063–1 0.25 0.5 0.361
    Posaconazole 0.031–1 0.125 0.5 0.196
    Caspofungin 2–16 8 16 8.903
    Micafungin 0.5–32 8 16 8.968
    Terbinafine 0.002–1 0.125 0.25 0.143
Environmental (n = 15)
    Fluconazole 16–256 64 256 82.133
    Flucytosine 2–64 16 64 24.8
    Amphotericin B 2–4 4 4 3.2
    Itraconazole 1–4 2 4 2
    Voriconazole 0.25–4 1 2 1.033
    Posaconazole 0.031–1 0.25 0.5 0.308
    Caspofungin 2–16 8 16 9.733
    Micafungin 1–32 4 16 7.933
    Terbinafine 0.063–0.5 0.125 0.25 0.171