FIG 2.

CQ functions through targeting histone proteins and its modifying enzymes. For a growth assay, the wild-type and different mutant yeast strains were grown until saturation. A 3-μl volume of each undiluted and 10-fold serially diluted culture was spotted onto control (untreated) plates or SCA plates containing 150 mM CQ. All plates were incubated at 30°C for 48 h and photographed.