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. 2014 Sep;58(9):5576–5580. doi: 10.1128/AAC.02681-14

TABLE 2.

Results for screening of bacteria recovered from TCF and CV for the presence of resistant strains at the end of therapy (day 11)

Treatment group (no. of samples)a No. of samples with resistant strains/total no. of samples (%)c from:
MIC (mg/liter) of resistant strains isolated
TCF CV
Control (21)b 0 0
CXA (20) 0 0
DAP (22) 35 35 2–3
RIF (19) 88 88 2–4
CXA + DAP (20)b 0 0
CXA + RIF (20) 0 0
a

CXA, cloxacillin; DAP, daptomycin; RIF, rifampin.

b

We did not detect subpopulations of daptomycin with MICs of ≥0.5 mg/liter among the wild-type strain (ATCC 29213) or among strains recovered ex vivo from the control or daptomycin-cloxacillin group.

c

Screening of resistant strains recovered from TCF and CV was performed using the methodology previously described (10,16), with agar plates containing 1 μg/ml cloxacillin, rifampin, or daptomycin. Results were interpreted as positive (some macroscopic growth) or negative (no growth).