TABLE 2.
Results for screening of bacteria recovered from TCF and CV for the presence of resistant strains at the end of therapy (day 11)
| Treatment group (no. of samples)a | No. of samples with resistant strains/total no. of samples (%)c from: |
MIC (mg/liter) of resistant strains isolated | |
|---|---|---|---|
| TCF | CV | ||
| Control (21)b | 0 | 0 | |
| CXA (20) | 0 | 0 | |
| DAP (22) | 35 | 35 | 2–3 |
| RIF (19) | 88 | 88 | 2–4 |
| CXA + DAP (20)b | 0 | 0 | |
| CXA + RIF (20) | 0 | 0 | |
CXA, cloxacillin; DAP, daptomycin; RIF, rifampin.
We did not detect subpopulations of daptomycin with MICs of ≥0.5 mg/liter among the wild-type strain (ATCC 29213) or among strains recovered ex vivo from the control or daptomycin-cloxacillin group.