TABLE 6.

Spearman's rank correlation coefficient and associated P values for the relationships between relative change in FEV₁ and FEV₁% predicted and absolute change in log₁₀ CFU of P. aeruginosa from baseline and dose or day 1 AUC

Day and value type	Relative change in FEV1		Relative change in FEV1% predicted		Absolute change (log10 CFU)
	Dose	Day 1 AUC	Dose	Day 1 AUC	Dose	Day 1 AUC
7
rs	0.351	0.357	0.332	0.342	−0.346	−0.32
P	<0.001	<0.001	<0.001	<0.001	<0.001	0.002
14
rs	0.388	0.362	0.343	0.321	−0.261	−0.263
P	<0.001	<0.001	<0.001	0.001	0.010	0.009
21
rs	0.294	0.282	0.263	0.255	−0.277	−0.25
P	0.003	0.005	0.009	0.011	0.006	0.014
28
rs	0.245	0.271	0.211	0.236	−0.264	−0.26
P	0.013	0.006	0.033	0.017	0.01	0.011
35 or 56a
rs	0.259	0.285	0.257	0.285	−0.218	−0.248
P	0.009	0.004	0.01	0.004	0.037	0.017

^aResults shown are for absolute change in log₁₀ CFU from baseline on day 35 and relative change in FEV₁ or FEV₁ % predicted from baseline on day 56.