FIG 9.
Expression of pneumolysin (ply) and autolysin (lytA). Lane 1, the 100-bp ladder; lane 2, effect of AMRI-SP1 infection (107 CFU per mouse) on untreated control group at 18 h postinfection; lanes 3 and 4, effect of monotherapy with either CRO (50 mg/kg) or LVX (150 mg/kg), respectively, at 24 h postinitiation of antibiotic treatment; lanes 5 to 8, effect of combination therapy on the expression of ply gene (a) and lytA gene (b) mRNAs at 2, 4, 8, 10, and 24 h posttherapy. GAPDH, glyceraldehyde-3-phosphate dehydrogenase.