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. 2014 Aug;21(8):1137–1144. doi: 10.1128/CVI.00207-14

FIG 4.

FIG 4

Ad5 and Ad5HVR48 induce lower levels of polyfunctional cytokine-secreting CD8+ T cells than Ad48. (A) Representative FACS plots showing the percentage of IFN-γ- and IL-2-expressing CD8+ T cells following AL11 peptide stimulation. (B) Mean fluorescence intensity indicating IFN-γ, TNF-α, and IL-2 expression following AL11 peptide in spleen and liver. (C) Absolute numbers of Gag-specific CD8+ T cells (DbAL11+) expressing IFN-γ, TNF-α, and IL-2 in the spleen and liver. Data are shown as means ± SEM. The horizontal lines at the top indicate P values of <0.05 using Student's t tests.