TABLE 1.
Physicochemical characterization of poly(anhydride) nanoparticles prepared by lyophilization or spray-drying
| Nanoparticle formulation | Result (mean ± SD) (n = 6) for: |
||||
|---|---|---|---|---|---|
| Size (nm) | Zeta potential (mV) | PE content (μg/mg NP) | Encapsulation efficiency (%) | Yield (%) | |
| NP-La | 201 ± 3 | −49 ± 2 | 80 ± 2 | ||
| NP-SDb | 172 ± 4 | −42 ± 4 | 63 ± 1 | ||
| NP-Raw-Lc | 161 ± 3 | −46 ± 2 | 31 ± 2 | 75 ± 5 | 73 ± 5 |
| NP-Ro-Ld | 155 ± 2 | −45 ± 5 | 30 ± 3 | 72 ± 6 | 76 ± 4 |
| NP-Raw-SDe | 150 ± 5 | −47 ± 2 | 35 ± 5 | 62 ± 3 | 60 ± 4 |
| NP-Ro-SDf | 143 ± 6 | −48 ± 3 | 32 ± 3 | 60 ± 4 | 61 ± 3 |
NP-L, unloaded lyophilized nanoparticles.
NP-SD, unloaded spray-dried nanoparticles.
NP-Raw-L, lyophilized nanoparticles loaded with raw peanut proteins.
NP-Ro-L, lyophilized nanoparticles loaded with roasted peanut proteins.
NP-Raw-SD, spray-dried nanoparticles loaded with raw peanut proteins.
NP-Ro-SD, spray-dried nanoparticles loaded with roasted peanut proteins.