FIG 8.

Numbers of FMDV-specific IgG-secreting cells in bone marrow. Mice (n = 8/group) were s.c. immunized with FMDV antigen plus physiological saline, RO, or RO containing GS-R (4 μg) on days 1 and 21. Bone marrow cells were prepared 8 weeks after boosting, and IgG-secreting cells were counted by an ELISPOT assay. The data are presented as means ± SD of FMDV-specific IgG-secreting cells standardized to responses per 2.4 million cells. Bars with different letters have statistically significant differences (P < 0.05).