TABLE 2.
Correlations between serum antibody responses and lesion and culture scores in pigs at bleeding (T3) and necropsy time (T4) using bPPD ELISA (anti-pig IgG and anti-pig IgM), DPP WildTB, and DPP VetTB tests
Antibody responses for test and time | Data type | Total lesion score | Thorax lesion score | Total culture score | Thorax culture scorea |
---|---|---|---|---|---|
OD for bPPD ELISA (time) | |||||
Anti-IgM (T3) | Correlation coefficient | 0.689b | 0.545c | 0.573c | 0.652b |
2-tailed significance | 0.001 | 0.016 | 0.01 | 0.002 | |
n | 19 | 19 | 19 | 19 | |
Anti-IgM (T4) | Correlation coefficient | 0.484c | 0.356 | 0.523c | 0.848b |
2-tailed significance | 0.036 | 0.135 | 0.022 | 0 | |
n | 19 | 19 | 19 | 19 | |
Anti-IgG (T3) | Correlation coefficient | 0.657b | 0.537c | 0.585b | 0.670b |
2-tailed significance | 0.002 | 0.018 | 0.009 | 0.002 | |
n | 19 | 19 | 19 | 19 | |
Anti-IgG (T4) | Correlation coefficient | 0.394 | 0.29 | 0.449 | 0.777b |
2-tailed significance | 0.095 | 0.229 | 0.054 | 0 | |
n | 19 | 19 | 19 | 19 | |
DPP for DPP WildTB mixture of MPB70 and MPB83 proteins at time: | |||||
T3 | Correlation coefficient | 0.436 | 0.272 | 0.630b | 0.479c |
2-tailed significance | 0.071 | 0.276 | 0.005 | 0.044 | |
n | 18 | 18 | 18 | 18 | |
T4 | Correlation coefficient | 0.382 | 0.211 | 0.537c | 0.348 |
2-tailed significance | 0.107 | 0.387 | 0.018 | 0.144 | |
n | 19 | 19 | 19 | 19 | |
DPP for DPP VetTB MPB83, CFP-10/ESAT-6 at time: | |||||
T3 | Correlation coefficient | 0.305 | 0.141 | 0.506b | 0.304 |
2-tailed significance | 0.204 | 0.566 | 0.027 | 0.206 | |
n | 19 | 19 | 19 | 19 | |
T4 | Correlation coefficient | 0.34 | 0.2 | 0.496c | 0.705b |
2-tailed significance | 0.154 | 0.411 | 0.031 | 0.001 | |
n | 19 | 19 | 19 | 19 |
Nonparametric Spearman correlations.
Significant at the 0.01 level.
Significant at the 0.05 level.