. 2014 Aug;88(15):8629–8639. doi: 10.1128/JVI.01257-14

TABLE 4.

Comparison of viral and immune characteristics between subjects without and with a history of virologic failure

Characteristic	No VF		VF		Wilcoxon P value	Adjusted P value^a
Characteristic	Mean	SD	Mean	SD	Wilcoxon P value	Adjusted P value^a
% CD3⁺	67.0	12.3	72.7	6.44	0.64	0.78
% CD4⁺	30.2	9.36	26.8	12.51	0.54	0.78
% CD8⁺	35.7	10.6	42.6	12.84	0.46	0.78
% HLA-DR⁺ CD38⁺ CD4⁺	19.5	10.6	16.2	6.14	0.78	0.78
% HLA-DR⁺ CD38⁺ CD8⁺	23.5	11.0	17.5	6.31	0.15	0.34
Plasma IL-6 level (pg/ml)	0.5	0.22	0.49	0.25	0.68	0.78
Baseline CD4⁺ STAT-3 activity	0.750	0.53	0.76	0.5	0.78	0.78
CD4⁺ STAT-3 activity in response to IL-6	−0.810	0.43	−0.82	0.44	0.78	0.78
env diversity (%)	2.57	1.62	3.66	1.72	0.12	0.31
env divergence (%)	10.1	0.60	9.32	0.96	0.28	0.56
pol diversity (%)	1.03	0.39	1.69	0.63	0.09	0.28
pol divergence (%)	3.97	0.29	4.22	0.61	0.69	0.78
LPV/r resistance score	0.140	0.38	7.37	20.3	0.56	0.78
3TC resistance score	1.12	1.45	40.5	28.4	0.008	0.09
ABC resistance score	4.43	6.31	36.7	26.8	0.01	0.09
EFV resistance score	0.690	1.29	19.0	26.8	0.08	0.28
Length of suppression (mo)	31	44.5	46	25.7	0.01	0.09
Duration of infection (yr)	11.6	5.01	18	4.6	0.04	0.17

Adjusted P values account for a false-discovery rate of 10%.