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. 2014 Aug;88(15):8407–8420. doi: 10.1128/JVI.01237-14

TABLE 3.

Relationship between the duration of infection, CNS histopathological lesions, viral burden, cellular targets, and anatomical compartmentalization in subtype B SHIVE macaquesa

Animal Time to AIDS Histopathologic lesion type(s) SIVp27 staining (morphology) Plasma and CSF compartmentalization
DG07 7 I +/− No
DE86 12 I, II ++ (Mϕ) Yes
DG08 20 I, II +++ (Mϕ) Yes
DN57 30 I, II +++ (Mϕ) No
ET94 39 I, II, III ++++ (Mϕ; microglia) No
a

The three main types of lesions and quantitative scoring for the presence of SIVp27 in macrophages (Mϕ) and microglia are shown in Fig. 1 and described in Tables 1 and 2.