FIG 6.

Radial distribution of salt bridge donors in EV1 protomer. (A) Single-protomer (colored) positioning with respect to the whole capsid (a half capsid is displayed). (B) The radial distribution of all atoms in EV1 protomer (PDB entry 1EV1) are depicted in the gray histogram to illustrate the density of the capsid shell. Colors indicate VP1 (blue), VP2 (red), VP3 (green), and VP4 (yellow), and the positioning of the salt bridge-forming amino acids (Lys and Arg) in a single protomer is shown, followed by their sequential positioning within these structural proteins. (C) The distribution of the salt bridge donors shows various degrees of connectivity within and between protomers. Interestingly, the inner protein VP4 forms connections mainly between protomers and one inner VP-VP connection.