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NS5A variants identified in the samatasvir-selected 719R-A cell linea
| Locus | Residue | % penetrance |
|---|---|---|
| K20 | M | 1 |
| N | 1 | |
| T | 6 | |
| K24b | E | 7 |
| I | 1 | |
| Q | 3 | |
| R | 3 | |
| T | 3 | |
| M28 | T | 7 |
| Q30 | E | 6 |
| H | 6 | |
| K | 12 | |
| R | 9 | |
| L31 | M | 8 |
| P | 1 | |
| P32 | L | 4 |
| Y93 | C | 4 |
| H | 51 | |
| N | 1 | |
| R | 1 | |
| S | 1 |
Only variants with significance to samatasvir resistance are displayed.
All variants at K24 were linked to a substitution at either M28, Q30, or Y93.
