TABLE 8.
Extent of resistance in samatasvir-selected genotype 1a replicon cell lines
Cell line | Mean fold change ± SD witha: |
||
---|---|---|---|
Samatasvir | Daclatasvir | IDX184 | |
719R-A | 3,100 ± 1,500 | 1,700 ± 500 | 0.81 ± 0.24 |
719R-B | 1,100 ± 200 | 630 ± 80 | 0.93 ± 0.19 |
719R-C | 1,300 ± 400 | 2,200 ± 1,900 | 1.6 ± 0.5 |
Mean fold changes ± standard deviations are for the mean results from three independent experiments for each samatasvir-selected cell line compared to their matched untreated control cell line.