TABLE 2.
Distribution of MICs for 1,380 bloodstream isolates of C. glabrata
| Antifungal | No. of isolates (no. with FKS mutation) at MIC (μg/ml)a: |
|||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 0.008 | 0.015 | 0.03 | 0.06 | 0.12 | 0.25 | 0.5 | 1 | 2 | 4 | 8 | 16 | |
| Anidulafungin | 2 | 77 | 636 (1) | 534 (2) | 83 (1) | 5 (3) | 8 (7) | 11 (10) | 15 (14) | 9 (9) | 0 | 0 |
| Caspofungin | 0 | 7 | 398 | 772 (1) | 141 (5) | 17 (3) | 9 (4) | 8 (7) | 6 (5) | 3 (3) | 3 (3) | 16 (16) |
| Micafungin | 110 | 939 | 260 | 13 (1) | 8 (3) | 16 (12) | 7 (5) | 7 (6) | 13 (13) | 7 (7) | 0 | 0 |
a
43 (3.1%), 45 (3.3%), and 50 (3.6%) isolates fell into the resistant range for anidulafungin, caspofungin, and micafungin, respectively.