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Structural rearrangements in the U13C, U20G, and 915G mutants. (A and B) Wild type (wt); (C and D) U13C; (E and F) U20G; (G and H) A915G. (Left) apo structures; (right) structures cocrystallized with streptomycin (orange sticks). The mutated residue in each structure is shown in blue.