TABLE 3.
Induced mutation to rifampin resistance in E. coli strain CC103
| Compound | Concn (μg/ml) | Avg mutation frequency/108 CFU ± SDa |
|---|---|---|
| Amixicile | 32 | 4.4 ± 2.7 |
| VPC162031 | 15 | 10 ± 3.5 |
| NTZ | 15 | 3.8 ± 3.1 |
| MTZ | 15 | 21 ± 1.4 |
| Nitrofurazone | 2.5 | 64 ± 32 |
| Control | 0 | 2.9 ± 1.3 |
Forward mutation to rifampin resistance was determined. Each value is the average of two independent experiments performed in triplicate.