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. 2014 Aug;58(8):4362–4370. doi: 10.1128/AAC.02754-13

FIG 6.

FIG 6

Plasma concentration-time profiles following a single oral administration of fexinidazole sulfoxide or fexinidazole sulfone to mice. Mice were dosed orally with 10 (●), 25 (△), 50 (◼), or 100 (◇) mg/kg of fexinidazole sulfoxide or fexinidazole sulfone. (A) Fexinidazole sulfoxide concentrations after administration of fexinidazole sulfoxide; (B) fexinidazole concentrations after administration of fexinidazole sulfoxide; (C) fexinidazole sulfone concentrations after administration of fexinidazole sulfoxide; (D) fexinidazole sulfone concentrations after administration of fexinidazole sulfone.