TABLE 3.
Characteristic LPS-binding parametersa of amphiphilic neamine derivatives obtained from Hill regression of the data given in Fig. 4a
Compound | EC50 (μM) | n (a.u.) | Ymax (%) |
---|---|---|---|
3′,6-di2NM | 4.9 | 0.8 | 68 |
3′,6-di2NP | 2.4 | 1.9 | 67 |
3′,6-di2NB | 2.1 | 2.3 | 68 |
3′,6-diNn | 1.7 | 2.7 | 94 |
3′,4′,6-tri2NM | 1.9 | 3.2 | 56 |
EC50, concentration for half probe displacement; n, Hill coefficient; a.u., arbitrary units; Ymax, maximal probe displacement.