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Amphotericin B uptake by mouse brain capillary endothelial cells was increased after coincubation with verapamil. (A) Mouse brain capillary endothelial cells were incubated with 2 μg/ml amphotericin B (AMB) with or without 100 μmol/liter verapamil (Ver). (B) Cells were coincubated with 2 μg/ml AMB and serial concentrations of Ver for 90 min. Data are means ± standard errors of the means (SEM). *, P < 0.05 compared to results at the same time point for the control (Student's t tests).
