MIC distributions and treatment outcome. (A) Vancomycin broth microdilution MIC distribution and treatment outcome. The statistical test performed was a Mann-Whitney U test. The failure rate distributions were 48% for 0.5 mg/liter, 66% for 1 mg/liter, 69% for 2 mg/liter, 100% for 4 mg/liter, and 100% for 8 mg/liter. (B) Vancomycin Etest MIC distribution and treatment outcome. The statistical test performed was a Mann-Whitney U test. The failure rate distributions were 0% for 0.38 mg/liter, 50% for 0.5 mg/liter, 76% for 0.75 mg/liter, 57% for 1 mg/liter, 68% for 1.5 mg/liter, 57% for 2 mg/liter, 100% for 3 mg/liter, 100% for 4 mg/liter, and 100% for 8 mg/liter. (C) Vancomycin PAP MIC distribution and treatment outcome. The statistical test performed was a Mann-Whitney U test. The failure rate distributions were 100% for 1 mg/liter, 38% for 1.5 mg/liter, 60% for 2 mg/liter, 62% for 3 mg/liter, 82% for 4 mg/liter, 86% for 8 mg/liter, and 100% for 16 mg/liter.