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VIM-7 structures. Shown are ribbon diagrams of the tVIM-7 wild type with the L1 (residues 60 to 66) and L3 (residues 223 to 240) loops in green (a), the tVIM-7-H224Y mutant (c), and the VIM-7-F218Y mutant (e) structures, with the corresponding calculated electrostatic surface potentials shown in panels b, c, and d. Ceftazidime (magenta) with a cyclic positively charged R2 group was docked and is shown in panels b to f.
