TABLE 3.

Oral efficacies of primaquine enantiomers and racemate against pneumocystis infection in mice

Compound	Dose, mg/kg/day (×21 days)	Activity, no. cured/no. treated (Giemsa stain)
Primaquine	10	5/10
	5	0/10
	2	0/10
(+)-Primaquine	10	9/10
	5	3/10
	2	0/10
(−)-Primaquine	10	0/10
	5	0/10
	2	0/10
TMP-SMX	50/250	9/10
NPC1161B	0.25	10/10
Control		0/10