TABLE 3.

Values^a for targeted and obtained pharmacokinetic parameters in SEV infection models

Regimenb	Peak concn (mg/liter)		Half-life (h)
	Targeted	Obtained	Targeted	Obtained
Daptomycin, 6 mg/kg q24h	98.6	102.5 ± 1.96	8	7.92 ± 0.18
Daptomycin, 10 mg/kg q24h	140.0	143.2 ± 1.94	8	7.87 ± 0.21
Linezolid, 600 mg q12h	21.0	21.9 ± 0.86	6	6.52 ± 0.87
Gentamicin, 1.3 mg/kg q12h	6.0	5.7 ± 0.51	2	2.08 ± 0.17
Rifampin, 300 mg q8h	10.5	11.0 ± 1.23	4	3.60 ± 0.50

^aMeans ± standard deviations.

^bBased on a 75-kg patient.