FIG 1.

Half-lives and percent-survival values of Cambodian Plasmodium falciparum isolates stratified by parasite subpopulation (A and B) or K13-propeller allele (C and D). The color codes for the WT, Y493H, C580Y, and R539T alleles used in panels A and B are indicated in panels C and D. All founder and mutant populations had significantly longer half-lives and higher percent-survival values than core and WT populations. P values were calculated using the Mann-Whitney test and are shown for significant differences among the founder or mutant populations.