TABLE 6.

Comparison of transcriptomes of the S. pneumoniae D39 ΔlacR and D39 wild-type strains grown in GM17

D39 taga	Functionb	Ratioc
SPD_0562	β-Galactosidase	4.9
SPD_1044	Lactose phosphotransferase system repressor (LacR)	−27.3
SPD_1046	6-Phospho-β-galactosidase (LacG)	1.0
SPD_1047	PTS system, lactose-specific IIBC components (LacE)	1.6
SPD_1048	PTS system, lactose-specific IIA component (LacF)	−1.3
SPD_1049	Transcription antiterminator (LacT)	−2.0
SPD_1050	Tagatose-1,6-diphosphate aldolase (LacD)	18.5
SPD_1051	Tagatose-6-phosphate kinase (LacC)	10.5
SPD_1052	Galactose-6-phosphate isomerase (LacB subunit)	33.0
SPD_1053	Galactose-6-phosphate isomerase (LacA subunit)	15.5

^aGene numbers refer to D39 locus tags.

^bD39 annotation/TIGR4 annotation (23, 25, 72).

^cRatio of the fold increase/decrease in the expression of genes in the ΔlacR strain compared to that in the wild type.