TABLE 3.
Modulated host proteins during coinfection with F. alocis and P. gingivalis
| Gene | Fold change | Annotation |
|---|---|---|
| Downregulated proteins | ||
| EIF4B | −3.675 | Eukaryotic translation initiation factor 4B |
| HIST1H1C | −2.742 | Histone cluster 1, H1c |
| HIST1H1E | −2.643 | Histone cluster 1, H1e |
| HIST1H2BL | −2.790 | Histone cluster 1, H2bl |
| PPIA | −3.307 | Peptidyl prolyl isomerase A (cyclophilin A) |
| VIM | −2.158 | Vimentin |
| SRSF1 | 4.049 | Serine/arginine-rich splicing factor 1 |
| PHB | Prohibin | |
| TRAP 1 | −1.035 | TNF receptor-associated protein 1 |
| PRDX1 | −1.219 | Peroxiredoxin 1 and 5 |
| PRDX5 | −1.201 | |
| Upregulated proteins | ||
| NACA | 2.310 | Nascent polypeptide-associated complex alpha subunit |
| IMPDH2 | 2.472 | Inosine-5′-monophosphate dehydrogenase 2 |
| AGF3 | 1.774 | AFG3-like protein 2 |
| RAB 10 | 1.128 | Member of RAS oncogene family |
| RAB 7A | 1.028 | Member of RAS oncogene family |
| ITGB1 | 1.356 | Integrin |
| PHB | 1.260 | Prohibitin |
| VCL | 2.189 | Vinculin |
| IGAAD | Granzyme A signaling proteins | |
| HSP10 | 2.160 | 10-kDa heat shock protein (mitochondrial) |
| LDHA | 1.516 | Isoform 1 of l-lactate dehydrogenase A chain |
| 1.512 | 46-kDa protein | |
| 1.907 | 26-kDa protein | |
| NACA | 2.310 | Nascent polypeptide-associated complex |
| KRT1 | 1.461 | Keratin type II cytoskeletal I |
| HNRPR | 1.728 | Heterogenous nuclear ribonucleoprotein R |