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. 2014 Aug;82(8):3261–3274. doi: 10.1128/IAI.01727-14

TABLE 4.

Metabolome variation in host protein during F. alocis coinfection

Expression category and pathway
Upregulated
    Ammonia production
    Urate biosynthesis through inosine 5′phosphate degradation
    Valine degradation
    Aspartate degradation
    l-Asparagine synthesis
    Glutaraldehyde CoA degradation
    Fatty acid biosynthesis
    Pentose phosphate pathway
    TCA cyclea
    Pyruvate fermentation to lactate
    Thioredoxin pathway
    Palmitate biosynthesis
    Purine de novo synthesis
Downregulated
    Sodium-independent glutamyl/arginine exchange
    l-Tryptophan transport
    Sucrose degradation
    Peptidyl proline synthesis
    Phosphoprotein synthesis
    Acetyl CoA biosynthesis from citrate
    Glycolysis
    NADH repair

aTCA, tricarboxylic acid.