FIG 4.

Persistence in different mouse strains. (A) Persistence of Y. pseudotuberculosis infection in different mouse strains infected with 10⁷ CFU/ml: C57BL/6 (three experiments, n = 26), BALB/c (seven experiments, n = 120), and FVB/N (seven experiments, n = 112). IVIS imaging was employed to determine if mice were infected at each time point. (B and C) Weight curves of FVB/N (B) and BALC/c (C) control mice or mice infected with 10⁷ CFU/ml of Y. pseudotuberculosis. Gray line, control mice (BALB/c, n = 7; FVB/N, n = 13); black line, persistent mice (BALB/c, n = 13; FVB/N, n = 11); black dashed line, cleared mice (BALB/c, n = 46; FVB/N, n = 22). (D and E) Weight curves of FVB/N (D) (n = 28) and BALC/c (E) (n = 29) mice infected with 10⁷ CFU/ml of Y. pseudotuberculosis that succumbed to infection.