. 2014 Aug;82(8):3186–3198. doi: 10.1128/IAI.02036-14

TABLE 6.

Infectivity of B. burgdorferi dbpA lysine point mutants in C3H/HeN mice during chronic infection

Strain	No. of days postinfection	No. of positive cultures/total					No. of positive mice/total
Strain	No. of days postinfection	Ear punch	Lymph nodes^a	Heart	Tibiotarsal	All sites	No. of positive mice/total
BbKH500	14	0/10^b	ND^c	ND	ND	0/10^b	0/10^b
	42	0/5	0/5^b	0/5^b	0/5	0/20^b	0/5^b
	70	0/5^b	0/5^b	0/5^b	0/5^b	0/20^b	0/5^b
BbKH501	14	10/10	ND	ND	ND	10/10^b	10/10^b
	42	3/5	4/5	5/5	3/5	15/20^b	5/5^b
	70	5/5	5/5	5/5	5/5	20/20^b	5/5^b
BbDbpA_K82A	14	0/10^b	ND	ND	ND	0/10^b	0/10^b
	42	0/5	0/5^b	0/5^b	0/5	0/20^b	0/5^b
	70	0/5^b	0/5^b	0/5^b	0/5^b	0/20^b	0/5^b
BbDbpA_K163A	14	0/10^b	ND	ND	ND	0/10^b	0/10^b
	42	0/5	0/5^b	0/5^b	0/5	0/20^b	0/5^b
	70	0/5^b	0/5^b	0/5^b	0/5^b	0/20^b	0/5^b
BbDbpA_K170A	14	0/10^b	ND	ND	ND	0/10^b	0/10^b
	42	0/5	0/5^b	0/5^b	0/5	0/20^b	0/5^b
	70	0/5^b	0/5^b	0/5^b	0/5^b	0/20^b	0/5^b

A single brachial and inguinal lymph node were collected from each mouse and cultured together.

The reductions in infection rates were statistically significantly different from BbKH501 (P ≤ 0.05 based on Fisher's exact test).

ND, not determined.