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The E. tarda T3SS is required for secretion of IL-1β but not TNF-α by BMDMs. BMDMs were infected with different strains for 6.5 h, and supernatants were collected for ELISA. Supernatant from a noninfected cell culture was used as a control. Values are means ± standard deviations (SD) for triplicate cultures. **, P < 0.01; ***, P < 0.001. (A) Secretion of IL-1β. (B) Secretion of TNF-α.
