FIG 6.

Dissemination of microbial burdens in monomicrobial and polymicrobial peritoneal infections with C. albicans and S. aureus. Mice (n = 5 mice/group) were inoculated i.p. with C. albicans (CA) and S. aureus (SA) as described in the legend to Fig. 1. At various time points postinoculation, mice were sacrificed, and the microbial burden in the brain was assessed in mice with monomicrobial and polymicrobial infections (C. albicans, open circles; S. aureus, closed circles). Results are expressed as the median CFU. Shown are cumulative data from two repeat experiments. Data were analyzed using the Mann-Whitney U test. °, P < 0.05 for S. aureus versus C. albicans-S. aureus.