TABLE 1.

Systemic leukocyte differential counts^a

Treatment	Mean cell count ± SEM (×106)
	MNL	PMNL	Total
Vehicle	3.3 ± 0.7	1.0 ± 0.2	4.3 ± 0.8
A-285222	3.6 ± 1.4	0.9 ± 0.2	4.5 ± 1.6
Vehicle and CLP	2.6 ± 0.3	0.5 ± 0.1b	3.2 ± 0.3
A-285222 and CLP	3.1 ± 0.8	1.7 ± 0.4c	4.8 ± 1.1

^aBlood was collected from vehicle- and A-285222 (0.15 mg/kg)-treated animals exposed to CLP for 24 h as well as from sham-operated mice. Cells were identified as monomorphonuclear (MNL) and polymorphonuclear (PMNL) cells. Data represent means ± SEM, ×10⁶ cells/ml. All experiments were repeated five times (n = 5 mice).

^bP < 0.05 versus sham-operated vehicle.

^cP < 0.05 versus CLP vehicle.