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. 2014 Aug;88(16):8981–8997. doi: 10.1128/JVI.00907-14

TABLE 2.

Clinical observations in H5N1 virus-infected animalsa

Virus strain Animal ID Clinical symptom(s)b
VN3028IIcl3 1 Decreased activity and mild depression on day 2
2
3 Mild coughing on day 10
VN30259 4
5 Mild huddling on day 5; nasal discharge on days 5 and 6
6
VN3040 7 Decreased activity on days 2, 3, 4, 5, 7, and 8; mild depression on days 3, 5, 7, and 8; mild coughing on day 8
8 Decreased activity on days 2 and 5; mild depression on day 5
9 Decreased activity and lying down on day 8; dying on day 9
VN3062 10
11 Mild huddling on day 6
12 Piloerection of body hair on days 1, 2, 4, 6, and 7
VN30408cl7 13 Nasal discharge on day 5
14
15
VN30850 16
17 Mild coughing on days 2 and 3; mild huddling on day 7
18 Piloerection of body hair on day 0; mild huddling on days 1, 2, and 3
a

Cynomolgus macaques were inoculated with 107.8 PFU thorough multiple routes and monitored twice daily throughout the study for each clinical parameter, i.e., posture, respiration, recumbency, attitude, and skin condition.

b

–, No clinical symptom observed.