TABLE 3.
Virus titers in respiratory swabs collected from H5N1 virus-infected animalsa
| Virus strain | Animal ID | Virus titer (log10 PFU/ml)b in: |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Bronchial brush at: |
Nasal swab at: |
||||||||||
| 1 dpi | 3 dpi | 5 dpi | 7 dpi | 9 dpi | 1 dpi | 3 dpi | 5 dpi | 7 dpi | 9 dpi | ||
| VN3028IIcl3 | 1 | 3.1 | 1.0 | – | – | – | – | – | 1.0 | – | – |
| 2 | – | 3.5 | – | – | – | – | – | – | – | – | |
| 3 | 1.3 | 1.3 | – | – | – | – | – | – | – | – | |
| VN30259 | 4 | 2.6 | 2.1 | 1.6 | – | – | 1.0 | 1.0 | 2.8 | 3.1 | – |
| 5 | 2.7 | 1.6 | – | – | – | 1.9 | – | – | 1.0 | – | |
| 6 | 2.5 | – | – | – | – | – | – | – | – | – | |
| VN3040 | 7 | 3.3 | 3.8 | 5.4 | 3.7 | 1.3 | 3.1 | 3.7 | – | – | 2.5 |
| 8 | 1.9 | 2.5 | 1.0 | 1.0 | – | 4.0 | 2.8 | – | 2.7 | – | |
| 9 | 3.7 | 3.8 | 5.2 | 3.9 | Died | 3.6 | 1.0 | 1.0 | 2.5 | Died | |
| VN3062 | 10 | 3.8 | 4.1 | 3.6 | – | – | 2.2 | 2.5 | – | – | – |
| 11 | 3.6 | 3.6 | 1.7 | 1.5 | – | 1.0 | 1.0 | – | – | – | |
| 12 | 4.2 | 4.3 | 3.3 | – | – | – | – | – | – | – | |
| VN30408cl7 | 13 | 2.0 | 1.0 | – | – | – | 1.5 | 1.7 | 1.6 | – | – |
| 14 | 4.3 | – | 2.2 | – | – | 1.8 | 2.7 | – | – | – | |
| 15 | – | – | – | – | – | – | – | – | – | – | |
| VN30850 | 16 | 3.2 | 3.3 | 2.0 | – | – | 1.0 | 1.0 | 3.4 | 2.5 | 1.0 |
| 17 | 4.8 | 1.9 | 1.6 | 2.2 | – | 4.0 | 1.5 | 1.5 | 1.9 | – | |
| 18 | 2.0 | 2.7 | 2.6 | 1.0 | – | 2.6 | 1.6 | 2.8 | 2.8 | 2.0 | |
a
Bronchial brushes and nasal swabs were collected every other day for virus titration after virus infection. Virus titers in the samples were determined by plaque assays in MDCK cells.
b
−, Virus not detected (detection limit = 1.0 log10 PFU/ml). dpi, days p.i.