TABLE 5.
Interactions between the ligands in the second sialic acid binding site and the NA molecules
| Ligands in the second sialic acid binding site and hydrogen bond distancea (Å) | |||
|---|---|---|---|
| N5 | N2Tyr406Asp | N6 | N9 |
| Ser367, 2.55; Ser370, 2.78; Ser372, 2.91; Asn400, 3.16, 2.76, 3.11. | Ser367, 2.53; Ser370, 2.67; Ser372, 2.81; Asn400, 3.18, 3.04, 2.71. | Ser367, 2.85; Ser370, 2.58, 3.29; Asn400, 3.25, 2.79, 2.94. | Ser367, 2.55; Ser370, 2.66; Ser372, 2.75; Asn400, 2.96, 2.90, 2.61; Lys432, 2.74. |
a
All hydrogen bond distances refer to molecule A of each structure.