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. 2014 Aug;88(16):8843–8852. doi: 10.1128/JVI.00424-14

FIG 2.

FIG 2

The activation of JNK upon viral-RNA transfection is RIG-I dependent. A549 cells were transfected with siRNA targeting RIG-I (siRig) or Mda5 (siMda5). Subsequently, the cells were transfected with viral RNA or cellular RNA, harvested after 4 h, and analyzed by Western blotting. sictr, control siRNA; nt, not transfected with siRNA.