FIG 3.

GVI3000-adjuvanted iFlu protects neonatally immunized mice from a lethal influenza virus challenge. Neonatal mice were immunized with iFlu only (n = 5) or with either GVI3000 (10⁵ IU) (n = 5) or alum (1:5) (n = 7). Included in the challenge were PBS-immunized mice (n = 8). All mice were intranasally challenged with a lethal dose of 10⁶ EID₅₀ of influenza A/PR/8/34 virus at 3 weeks after immunization. (A to F) Mice were monitored for mortality (A and B) and weight (C to F) for 7 days after the challenge.