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Type I IFN production induced by poly(I·C) and Toca 511 in CCD-1070Sk fibroblasts and U87-MG glioma cells. Cells were transfected with poly(I·C) at 10 μg/ml or infected with Toca 511 at an MOI of 10. Culture supernatants from untreated and poly(I·C)- or Toca 511-treated cells were collected 8 h posttreatment for an ELISA to measure the amount of IFN-β (A) and IFN-α (B), respectively. Data shown represent means ± standard deviations (n = 3).
