TABLE 1.
Parameters used for simulation of the model in equation 1a
| Parameter | Definition | Unit of measure | Value | Reference(s) |
|---|---|---|---|---|
| λ | No. of newly produced CD4+ T cells (per μl) | Day−1 | 8 | 31 |
| δT | Death rate of CD4+ T cells | Day−1 | 0.01 | 32 |
| δ̃I | Death rate of productively infected cells | Day−1 | 1 | 31, 42–44 |
| c | Viral clearance rate | Day−1 | 23 | 33 |
| β | Infection rate per virion | Day−1 | 10−4 | |
| E | Density of HIV-specific CTL | Cells ml−1 | 225 (0.075) | 34–36 |
a
The different parameters for simulation of HIV-1 dynamics during the chronic phase of infection were obtained from the indicated references. The number in brackets represents the frequency of HIV-specific CTL.