FIG 3.

Anti-SIV T cell responses postvaccination. (A) Magnitude of IFN-γ⁺ CD8 T cell responses. (B) Breadth of anti-SIV CD8 T cell responses. Breadth is measured using 13 Gag peptide pools and 11 Env peptide pools. These pools consist of a total of 125 Gag peptides and 225 Env peptides. (C) Percent proliferating Gag-specific CD8 T cells at 1 week after the second MVA, as measured by CFSE dilution. (D) Magnitude of IFN-γ⁺ CD4 T cell responses. (E) Breadth of anti-SIV CD4 T cell responses. (F) Boolean analysis of anti-SIV CD4 T cell responses at 1 week after the first MVA. Capital letters indicate the coexpression patterns for IFN-γ (I), IL-2 (L), and/or TNF-α (T).