TABLE 2.
Parameter | Statistic | Baseline pVL | Nef CD4 downregulation | Nef HLA downregulation | Nef infectivity enhancement |
---|---|---|---|---|---|
Baseline eDPI | R | −0.77 | −0.52 | −0.85 | 0.19 |
P | 0.007 | 0.1 | 0.004 | 0.6 | |
Baseline pVL | R | 0.48 | 0.81 | 0.01 | |
P | 0.2 | 0.01 | 1.0 | ||
CD4 downregulation | R | 0.74 | −0.05 | ||
P | 0.02 | 0.9 | |||
HLA downregulation | R | 0.15 | |||
P | 0.7 |
Abbreviations: pVL, plasma viral load; HLA, human leukocyte antigen; eDPI, estimated days postinfection. Data represent Spearman R and P values. Significant associations are highlighted in bold type.