Table 1.

Patient characteristics

Patient	Age	Sex	Immunodeficiency	Mutation	Country of origin	Age at disease onset	Isolated mycobacterial strains	Disease localization	Interferon treatment
1	22	female	complete IFNγR1 deficiency	compound heterozygous 373(+1)g→t 202(-1)g→c	US	1 yr	MAC M. fortuitum M. kansasii M. abscessus	bone bone marrow liver lung lymph nodes	IFNα2b
2	19	Male	complete IFNγR1 deficiency	homozygous 22delC	Pakistan	2 yr	MAC M. abscessus	blood liver lung lymph nodes skin	IFNα2b → PEG IFN alpha
3	5	Male	partial IFNγR1 deficiency	homozygous I87T	Chile	2 mo	M. bovis BCG	bone brain lung lymph nodes pleura skin	IFNα2b & IFNγ
4	52	female	partial IFNγR1 deficiency	heterozygous 818del4	US	20 yr	MAC M. fortuitum M. avium X-cluster	Maxillary sinus skin palate lymph nodes	IFNα2b & IFNγ