Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Screening of Solvents.[a]
| |||
|---|---|---|---|
| Entry | Solvent | Time (h) | Yield (%)/[b] (α:β)[c] |
| 1 | CH2Cl2 | 1 | 85 (30:1) |
| 2 | THF | 3 | 49 (19:1) |
| 3 | MTBE | 1.5 | 50 (16:1) |
| 4 | Dioxane | 5 | 67 (15:1) |
| 5 | Toluene | 2 | 75 (20:1) |
| 6 | Trifluorotoluene | 1.25 | 67 (13:1) |
The rearrangements were performed at 0.2 M in CH2Cl2 with 2 mol% of Ni(dppe)(OTf)2.
Isolated Yield.
1H NMR ratio.
